node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70327.1 | ABK71134.1 | MSMEG_6394 | MSMEG_6388 | Conserved hypothetical protein. | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | 0.849 |
ABK70327.1 | ABK72375.1 | MSMEG_6394 | MSMEG_6387 | Conserved hypothetical protein. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.849 |
ABK70327.1 | ABK74530.1 | MSMEG_6394 | MSMEG_6372 | Conserved hypothetical protein. | Identified by match to protein family HMM PF04138. | 0.654 |
ABK70327.1 | ABK75671.1 | MSMEG_6394 | MSMEG_6400 | Conserved hypothetical protein. | Probable conserved transmembrane protein. | 0.875 |
ABK70327.1 | aftA | MSMEG_6394 | MSMEG_6386 | Conserved hypothetical protein. | Membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf. | 0.763 |
ABK70327.1 | aftC | MSMEG_6394 | MSMEG_2785 | Conserved hypothetical protein. | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.776 |
ABK71134.1 | ABK70327.1 | MSMEG_6388 | MSMEG_6394 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Conserved hypothetical protein. | 0.849 |
ABK71134.1 | ABK72375.1 | MSMEG_6388 | MSMEG_6387 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.835 |
ABK71134.1 | ABK74530.1 | MSMEG_6388 | MSMEG_6372 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Identified by match to protein family HMM PF04138. | 0.806 |
ABK71134.1 | ABK75671.1 | MSMEG_6388 | MSMEG_6400 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Probable conserved transmembrane protein. | 0.911 |
ABK71134.1 | acpP | MSMEG_6388 | MSMEG_4326 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Acyl carrier protein; Acyl carrier protein involved in meromycolate extension. | 0.985 |
ABK71134.1 | aftA | MSMEG_6388 | MSMEG_6386 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf. | 0.984 |
ABK71134.1 | aftC | MSMEG_6388 | MSMEG_2785 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.811 |
ABK71134.1 | dprE1 | MSMEG_6388 | MSMEG_6382 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Oxidoreductase, FAD-binding; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate chann [...] | 0.801 |
ABK71134.1 | dprE2 | MSMEG_6388 | MSMEG_6385 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Putative oxidoreductase in MprA 5'region; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'su [...] | 0.851 |
ABK71134.1 | rpsL | MSMEG_6388 | MSMEG_1398 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.836 |
ABK72375.1 | ABK70327.1 | MSMEG_6387 | MSMEG_6394 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Conserved hypothetical protein. | 0.849 |
ABK72375.1 | ABK71134.1 | MSMEG_6387 | MSMEG_6388 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | 0.835 |
ABK72375.1 | ABK74530.1 | MSMEG_6387 | MSMEG_6372 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Identified by match to protein family HMM PF04138. | 0.895 |
ABK72375.1 | ABK75671.1 | MSMEG_6387 | MSMEG_6400 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable conserved transmembrane protein. | 0.908 |