STRINGSTRING
ABK72372.1 ABK72372.1 sucA sucA pknB pknB ABK73081.1 ABK73081.1 ABK75618.1 ABK75618.1 ABK73680.1 ABK73680.1 ABK69959.1 ABK69959.1 ABK73124.1 ABK73124.1 ABK75001.1 ABK75001.1 ABK74246.1 ABK74246.1 ABK75713.1 ABK75713.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK72372.1Conserved hypothetical protein. (129 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 
 0.920
pknB
Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA.
  
 
 0.887
ABK73081.1
Antigen 34 kDa.
   
 0.634
ABK75618.1
DNA repair exonuclease; Identified by match to protein family HMM PF00149.
   
 0.628
ABK73680.1
Serine esterase, cutinase family protein; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
  0.585
ABK69959.1
Cutinase superfamily protein; Identified by match to protein family HMM PF01083.
  
  0.583
ABK73124.1
Serine esterase, cutinase family protein; Identified by match to protein family HMM PF01083.
  
  0.582
ABK75001.1
Serine esterase, cutinase family protein; Identified by match to protein family HMM PF01083.
  
  0.582
ABK74246.1
Serine esterase, cutinase family protein; Identified by match to protein family HMM PF01083.
  
  0.582
ABK75713.1
Probable cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
  0.581
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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