STRINGSTRING
ABK69860.1 ABK69860.1 ABK74864.1 ABK74864.1 ABK72752.1 ABK72752.1 ABK75307.1 ABK75307.1 ABK69583.1 ABK69583.1 ABK75421.1 ABK75421.1 mutM mutM ABK72686.1 ABK72686.1 mutY mutY ku ku ABK76222.1 ABK76222.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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Experiments
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[Homology]
Score
ABK69860.1Identified by match to protein family HMM PF01261. (273 aa)    
Predicted Functional Partners:
ABK74864.1
Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.
 
  
 0.887
ABK72752.1
Identified by match to protein family HMM PF01261.
 
   
0.780
ABK75307.1
Sugar phosphate isomerase/epimerase; Identified by match to protein family HMM PF01261.
  
    0.732
ABK69583.1
Fumarylacetoacetate; Identified by match to protein family HMM PF01557.
   
  
 0.700
ABK75421.1
Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
 
    0.621
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Acts on oxidized purines, such as 7,8-dihydro-8- oxoguanine (8-oxoG) when paired with C, G or T. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates; Belongs to the FPG family.
  
  
 0.608
ABK72686.1
IolD protein; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
  
  
 0.604
mutY
Base excision DNA repair protein, HhH-GPD family protein; Adenine glycosylase active on G:A and C:A mispairs, as well as processing 7,8-dihydro-8-oxoguanine:A (8-oxoG) mismatches. Belongs to the Nth/MutY family.
  
  
 0.592
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) repair enzyme which repairs blunt-end and 5'-overhang double strand breaks (DSB) with about 50% fidelity, and DSB with non-complementary 3' ends. Plays a partial role in NHEJ on 3'-overhang repair of complementary ends. NHEJ repairs DSB with blunt ends and 5' overhangs with a high level of nucleotide insertion/deletion, without a need for microhomology. This protein but not LigD also suppresses homologous recombination. Overexpression dramatically increases the efficiency of NHEJ with no effect on repair fidelity.
   
  
 0.591
ABK76222.1
Maleylacetate reductase; Identified by match to protein family HMM PF00465.
 
    0.586
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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