STRINGSTRING
ABK70749.1 ABK70749.1 thyA thyA ABK73144.1 ABK73144.1 ABK70195.1 ABK70195.1 ABK72446.1 ABK72446.1 ABK74143.1 ABK74143.1 ABK74887.1 ABK74887.1 ABK72525.1 ABK72525.1 ABK71801.1 ABK71801.1 ABK71216.1 ABK71216.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK70749.1Conserved hypothetical protein. (199 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.638
ABK73144.1
Beta-lactamase; Identified by match to protein family HMM PF00144.
  
  
 0.571
ABK70195.1
Secreted protein.
 
 
 0.493
ABK72446.1
AraC-family protein transcriptional regulator; Identified by match to protein family HMM PF00165; match to protein family HMM PF01965.
 
    0.445
ABK74143.1
Riboflavin biosynthesis protein RibD C- domain protein; Identified by match to protein family HMM PF01872.
  
    0.442
ABK74887.1
Acetyltransferase.
 
    0.440
ABK72525.1
Integral membrane protein.
  
    0.436
ABK71801.1
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005.
 
  
 0.434
ABK71216.1
Transcriptional regulator, AraC family protein; Identified by match to protein family HMM PF00165; match to protein family HMM PF01965.
 
    0.430
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.