node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS37984.1 | purL | MexAM1_META1p0011 | MexAM1_META1p0010 | BolA-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the BolA/IbaG family. | Phosphoribosylformylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.956 |
purD | purE | MexAM1_META1p4244 | MexAM1_META1p1936 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purD | purF | MexAM1_META1p4244 | MexAM1_META1p4314 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.999 |
purD | purH | MexAM1_META1p4244 | MexAM1_META1p2535 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.975 |
purD | purK | MexAM1_META1p4244 | MexAM1_META1p1937 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.953 |
purD | purL | MexAM1_META1p4244 | MexAM1_META1p0010 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylformylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.959 |
purD | purM | MexAM1_META1p4244 | MexAM1_META1p2045 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylaminoimidazole synthetase (AIR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |
purD | purN | MexAM1_META1p4244 | MexAM1_META1p2044 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | MexAM1_META1p4244 | MexAM1_META1p0424 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.951 |
purD | yexA | MexAM1_META1p4244 | MexAM1_META1p0423 | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.910 |
purE | purD | MexAM1_META1p1936 | MexAM1_META1p4244 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | 0.997 |
purE | purF | MexAM1_META1p1936 | MexAM1_META1p4314 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.975 |
purE | purH | MexAM1_META1p1936 | MexAM1_META1p2535 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.973 |
purE | purK | MexAM1_META1p1936 | MexAM1_META1p1937 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.999 |
purE | purL | MexAM1_META1p1936 | MexAM1_META1p0010 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylformylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.961 |
purE | purM | MexAM1_META1p1936 | MexAM1_META1p2045 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylaminoimidazole synthetase (AIR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.987 |
purE | purN | MexAM1_META1p1936 | MexAM1_META1p2044 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.956 |
purE | purQ | MexAM1_META1p1936 | MexAM1_META1p0424 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.966 |
purE | yexA | MexAM1_META1p1936 | MexAM1_META1p0423 | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.912 |
purF | purD | MexAM1_META1p4314 | MexAM1_META1p4244 | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylglycinamide synthetase (GAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. | 0.999 |