STRINGSTRING
mdcD mdcD mdcE mdcE mdcA mdcA mdcC mdcC ACS38002.1 ACS38002.1 ACS41747.1 ACS41747.1 mdcB mdcB accA accA accB accB ACS37995.1 ACS37995.1 fabD fabD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdcDMalonate decarboxylase, beta-subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (310 aa)    
Predicted Functional Partners:
mdcE
Malonate decarboxylase, gamma subunit; Function of strongly homologous gene; enzyme.
 
 0.999
mdcA
Malonate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme.
 
 
 0.989
mdcC
Malonate decarboxylase acyl carrier protein (Malonate decarboxylase delta subunit); Function of strongly homologous gene; enzyme.
  
 0.986
ACS38002.1
[acyl-carrier-protein] S-malonyltransferase; Function of strongly homologous gene; enzyme.
 
  
 0.986
ACS41747.1
ATP-dependent urea carboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.977
mdcB
2'-(5''-triphosphoribosyl)-3'-dephosphocoenzyme- A synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.
 
  
 0.969
accA
acetyl-CoA carboxylase, carboxytransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.958
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.908
ACS37995.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.863
fabD
malonyl-CoA-[acyl-carrier-protein] transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.831
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.