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rrm rrm ACS38131.1 ACS38131.1 rplO rplO rluD rluD rplM rplM rnr rnr rnhB rnhB engB engB rplC rplC ACS40671.1 ACS40671.1 trmE trmE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rrmrRNA methylase; Function of strongly homologous gene; enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (268 aa)    
Predicted Functional Partners:
ACS38131.1
Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family.
 
 
 0.842
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
   0.837
rluD
Ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
 
 0.822
rplM
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.818
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
 
 0.803
rnhB
RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.795
engB
Putative GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
 
 0.794
rplC
50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 
 0.787
ACS40671.1
Pseudouridine synthase; Function of strongly homologous gene; enzyme.
 
 
 0.787
trmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 
 0.785
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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