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coxA coxA ACS38081.1 ACS38081.1 ACS38083.1 ACS38083.1 coxC coxC coxB coxB cyoC cyoC ACS38084.1 ACS38084.1 petB petB cyoA cyoA coxE coxE nuoM nuoM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
coxACytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (563 aa)    
Predicted Functional Partners:
ACS38081.1
Putative Cytochrome c oxidase, subunit II (coxB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.999
ACS38083.1
Putative Cytochrome c oxidase, subunit III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 0.999
coxC
Cytochrome c oxidase subunit III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
coxB
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 0.999
cyoC
Cytochrome o ubiquinol oxidase, subunit III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.984
ACS38084.1
Putative cytochrome oxidase subunit IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
  0.978
petB
Ubiquinol-cytochrome c reductase complex, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.978
cyoA
Cytochrome o ubiquinol oxidase subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.971
coxE
Heme O synthase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.961
nuoM
NADH-quinone oxidoreductase chain M (NADH dehydrogenase I, chain M); Function of strongly homologous gene; enzyme.
  
 
 0.953
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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