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kdpC kdpC kdpA kdpA kdpB kdpB kdpD kdpD ACS38091.1 ACS38091.1 kdpE kdpE ACS42484.1 ACS42484.1 mxbD mxbD recF recF murA murA ACS38093.1 ACS38093.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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kdpCPotassium-transporting ATPase KdpC subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (201 aa)    
Predicted Functional Partners:
kdpA
Potassium-transporting ATPase potassium-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 0.999
kdpB
Potassium-transporting ATPase ATP-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 0.999
kdpD
Sensory histidine kinase in two-component regulatory system wtih KdpE; Regulation of potassium translocation in E coli; Function of strongly homologous gene; enzyme.
 
  
 0.991
ACS38091.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
  0.941
kdpE
Two-component system, OmpR family, KDP operon response regulator KdpE; Function of strongly homologous gene; regulator.
 
  
 0.883
ACS42484.1
Putative histidine kinase, Putative HK, ATPase and Sensor Domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.840
mxbD
Two-component transcriptional regulator, sensor kinase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.837
recF
Putative RecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
      
 0.731
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
      
 0.609
ACS38093.1
Hypothetical protein; No homology to any previously reported sequences.
       0.537
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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