node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38131.1 | obg | MexAM1_META1p0168 | MexAM1_META1p4852 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.748 |
ACS38131.1 | rplC | MexAM1_META1p0168 | MexAM1_META1p2153 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.825 |
ACS38131.1 | rplM | MexAM1_META1p0168 | MexAM1_META1p2739 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.809 |
ACS38131.1 | rplO | MexAM1_META1p0168 | MexAM1_META1p2173 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.805 |
ACS38131.1 | rplQ | MexAM1_META1p0168 | MexAM1_META1p2166 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure. | 0.716 |
ACS38131.1 | rplU | MexAM1_META1p0168 | MexAM1_META1p4856 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.778 |
ACS38131.1 | rplX | MexAM1_META1p0168 | MexAM1_META1p2181 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.786 |
ACS38131.1 | rrm | MexAM1_META1p0168 | MexAM1_META1p0057 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | rRNA methylase; Function of strongly homologous gene; enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.842 |
ACS38131.1 | rsfS | MexAM1_META1p0168 | MexAM1_META1p3075 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | Conserved hypothetical protein, Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.734 |
ACS38131.1 | trmE | MexAM1_META1p0168 | MexAM1_META1p1471 | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.789 |
obg | ACS38131.1 | MexAM1_META1p4852 | MexAM1_META1p0168 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridine synthase, RluD; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RluA family. | 0.748 |
obg | rplC | MexAM1_META1p4852 | MexAM1_META1p2153 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.724 |
obg | rplM | MexAM1_META1p4852 | MexAM1_META1p2739 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.800 |
obg | rplO | MexAM1_META1p4852 | MexAM1_META1p2173 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.778 |
obg | rplQ | MexAM1_META1p4852 | MexAM1_META1p2166 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure. | 0.793 |
obg | rplU | MexAM1_META1p4852 | MexAM1_META1p4856 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.950 |
obg | rplX | MexAM1_META1p4852 | MexAM1_META1p2181 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.801 |
obg | rrm | MexAM1_META1p4852 | MexAM1_META1p0057 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | rRNA methylase; Function of strongly homologous gene; enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.573 |
obg | rsfS | MexAM1_META1p4852 | MexAM1_META1p3075 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein, Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.864 |
obg | trmE | MexAM1_META1p4852 | MexAM1_META1p1471 | Small GTP-binding protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.496 |