Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS41931.1 | ccr | MexAM1_META1p4295 | MexAM1_META1p0178 | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | 0.761 |
| ACS41931.1 | ecm | MexAM1_META1p4295 | MexAM1_META1p0180 | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | 0.787 |
| ACS41931.1 | ibd2 | MexAM1_META1p4295 | MexAM1_META1p2223 | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | isobutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme. | 0.541 |
| ACS41931.1 | meaC | MexAM1_META1p4295 | MexAM1_META1p4153 | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | Mesaconyl-CoA hydratase; Part of the glyoxylate regeneration cycle that is essential for growth on C1 and C2 compounds; Function experimentally demonstrated in the studied strain; enzyme. | 0.983 |
| ACS41931.1 | pccB | MexAM1_META1p4295 | MexAM1_META1p0172 | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | propionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.913 |
| ccr | ACS41931.1 | MexAM1_META1p0178 | MexAM1_META1p4295 | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | 0.761 |
| ccr | ecm | MexAM1_META1p0178 | MexAM1_META1p0180 | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | 0.957 |
| ccr | epi | MexAM1_META1p0178 | MexAM1_META1p0839 | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | ethylmalonyl-CoA/methylmalonyl-CoA epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.966 |
| ccr | ibd2 | MexAM1_META1p0178 | MexAM1_META1p2223 | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | isobutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme. | 0.812 |
| ccr | meaC | MexAM1_META1p0178 | MexAM1_META1p4153 | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | Mesaconyl-CoA hydratase; Part of the glyoxylate regeneration cycle that is essential for growth on C1 and C2 compounds; Function experimentally demonstrated in the studied strain; enzyme. | 0.885 |
| ecm | ACS41931.1 | MexAM1_META1p0180 | MexAM1_META1p4295 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. | 0.787 |
| ecm | ccr | MexAM1_META1p0180 | MexAM1_META1p0178 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | crotonyl-CoA carboxylase/reductase; Function experimentally demonstrated in the studied strain; enzyme. | 0.957 |
| ecm | epi | MexAM1_META1p0180 | MexAM1_META1p0839 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | ethylmalonyl-CoA/methylmalonyl-CoA epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.995 |
| ecm | ibd2 | MexAM1_META1p0180 | MexAM1_META1p2223 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | isobutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme. | 0.965 |
| ecm | mcmA | MexAM1_META1p0180 | MexAM1_META1p5251 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.978 |
| ecm | mcmB | MexAM1_META1p0180 | MexAM1_META1p2390 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | methylmalonyl-CoA beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.982 |
| ecm | meaB | MexAM1_META1p0180 | MexAM1_META1p0188 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | methylmalonyl-CoA mutase accessory protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |
| ecm | meaC | MexAM1_META1p0180 | MexAM1_META1p4153 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | Mesaconyl-CoA hydratase; Part of the glyoxylate regeneration cycle that is essential for growth on C1 and C2 compounds; Function experimentally demonstrated in the studied strain; enzyme. | 0.918 |
| ecm | metH | MexAM1_META1p0180 | MexAM1_META1p1494 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.834 |
| ecm | pccB | MexAM1_META1p0180 | MexAM1_META1p0172 | ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for M.extorquens growth on one- and two-carbon compounds such as ethylamine, methanol or ethanol as sole carbon source. This enzyme acts as a regulatory metabolic control point in this pathway, that allows M.extorquens to efficiently restore metabolic balance when challenged with a sudden change in the growth substrate. | propionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.886 |
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