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ribF ribF ribE ribE truB truB ribE-2 ribE-2 ssuE ssuE ACS39323.1 ACS39323.1 ribD ribD cmk cmk coaD coaD pyrH pyrH gmk gmk
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ribFPutative riboflavin biosynthesis protein ribF; Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ribF family. (337 aa)    
Predicted Functional Partners:
ribE
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.977
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.954
ribE-2
Riboflavin synthase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
 0.934
ssuE
NAD(P)H-dependent FMN reductase; Function of strongly homologous gene; enzyme.
    
 0.910
ACS39323.1
Putative acid phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
  0.900
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.899
cmk
Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme.
 
  
 0.843
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
   
 0.796
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.704
gmk
Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP.
 
  
 0.687
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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