STRINGSTRING
ACS38288.1 ACS38288.1 ACS40512.1 ACS40512.1 gck gck sga sga hprA hprA ACS38623.1 ACS38623.1 mcl mcl sga-2 sga-2 ACS41931.1 ACS41931.1 ACS42846.1 ACS42846.1 eda eda
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS38288.1Putative 2-hydroxyacid dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)    
Predicted Functional Partners:
ACS40512.1
Putative glycerate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.939
gck
Glycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.934
sga
Serine-glyoxylate aminotransferase (SGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.928
hprA
Hydroxypyruvate reductase, NAD(P)H-dependent; Plays a central role in assimilation of carbon. It converts hydroxypyruvate to glycerate as a key step in the serine cycle, and may also play an important role in C2 reactions, by interconverting glyoxylate and glycolate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.923
ACS38623.1
Putative glycolate oxidase (glcD-like), FAD-linked subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.921
mcl
malyl-CoA lyase/beta-methylmalyl-CoA lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.921
sga-2
Serine-glyoxylate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.919
ACS41931.1
Putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.916
ACS42846.1
Putative glycolate oxidase subunit GlcE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.910
eda
Multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.906
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.