STRINGSTRING
fabD fabD fabF fabF ACS42598.1 ACS42598.1 fabB fabB ACS39663.1 ACS39663.1 fabH fabH ACS40752.1 ACS40752.1 ACS40754.1 ACS40754.1 fabG fabG fabI fabI fabI-2 fabI-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
fabDmalonyl-CoA-[acyl-carrier-protein] transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (294 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.999
ACS42598.1
Putative 3-oxoacyl-[acyl-carrier-protein] synthase (fabF-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.999
fabB
3-oxoacyl-[acyl-carrier-protein] synthase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.998
ACS39663.1
Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
0.996
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.995
ACS40752.1
Putative 3-oxoacyl-(Acyl-carrier-protein) synthase III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.993
ACS40754.1
Putative keto/oxo acyl-ACP synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.993
fabG
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.990
fabI
Enoyl-[acyl-carrier-protein] reductase (NADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.984
fabI-2
Enoyl-[acyl-carrier-protein] reductase (NADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.984
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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