STRINGSTRING
depA depA phaC phaC ACS41800.1 ACS41800.1 depB depB ACS42331.1 ACS42331.1 phaR phaR ACS38361.1 ACS38361.1 regS regS regR regR ibd2 ibd2 epi epi
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
depAIntracellular PHB depolymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (414 aa)    
Predicted Functional Partners:
phaC
Polyhydroxyalkanoate synthase subunit PhaC; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.972
ACS41800.1
Intracellular PHB depolymerase, polyhydroxyalkanoate depolymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 
0.907
depB
PHB depolymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 
0.902
ACS42331.1
Metal-dependent phosphohydrolase; Function of strongly homologous gene; enzyme.
      
 0.662
phaR
Putative regulator for granule-associated proteins, PHB biosynthesis and acetyl-CoA flux; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   
 0.597
ACS38361.1
Putative metal-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.573
regS
Two component sensor histidine kinase, RegS; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.566
regR
Two-component transcriptional regulator RegR, Fis family; Function of homologous gene experimentally demonstrated in an other organism; regulator.
       0.496
ibd2
isobutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme.
      
 0.448
epi
ethylmalonyl-CoA/methylmalonyl-CoA epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.405
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (16%) [HD]