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thiG thiG thiO thiO thiS thiS thiE thiE thiC thiC moeB moeB thiE-2 thiE-2 thiD thiD dxs dxs dxs-2 dxs-2 ACS40459.1 ACS40459.1
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second shell of interactors
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Predicted Interactions
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textmining
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protein homology
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thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (273 aa)    
Predicted Functional Partners:
thiO
Glycine oxidase; Function of strongly homologous gene; enzyme.
 
 0.999
thiS
Thiamin biosynthesis proteinsulfur carrier) ThiS; Function of strongly homologous gene; factor.
 
 
 0.995
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
  
 0.989
thiC
Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.988
moeB
Molybdopterin synthase sulfurylase; Function of strongly homologous gene; enzyme.
  
 0.957
thiE-2
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.944
thiD
Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of strongly homologous gene; enzyme.
 
  
 0.933
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.920
dxs-2
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.920
ACS40459.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.861
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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