node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40154.1 | ACS40459.1 | MexAM1_META1p2371 | MexAM1_META1p2693 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.605 |
ACS40154.1 | ACS42507.1 | MexAM1_META1p2371 | MexAM1_META1p4898 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.506 |
ACS40154.1 | moeB | MexAM1_META1p2371 | MexAM1_META1p1526 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Molybdopterin synthase sulfurylase; Function of strongly homologous gene; enzyme. | 0.652 |
ACS40154.1 | thiC | MexAM1_META1p2371 | MexAM1_META1p1503 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.842 |
ACS40154.1 | thiD | MexAM1_META1p2371 | MexAM1_META1p4915 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of strongly homologous gene; enzyme. | 0.982 |
ACS40154.1 | thiE | MexAM1_META1p2371 | MexAM1_META1p0427 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.900 |
ACS40154.1 | thiE-2 | MexAM1_META1p2371 | MexAM1_META1p4916 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.900 |
ACS40154.1 | thiG | MexAM1_META1p2371 | MexAM1_META1p0428 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.847 |
ACS40154.1 | thiS | MexAM1_META1p2371 | MexAM1_META1p0429 | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thiamin biosynthesis proteinsulfur carrier) ThiS; Function of strongly homologous gene; factor. | 0.826 |
ACS40459.1 | ACS40154.1 | MexAM1_META1p2693 | MexAM1_META1p2371 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.605 |
ACS40459.1 | ACS42507.1 | MexAM1_META1p2693 | MexAM1_META1p4898 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.633 |
ACS40459.1 | thiC | MexAM1_META1p2693 | MexAM1_META1p1503 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.830 |
ACS40459.1 | thiD | MexAM1_META1p2693 | MexAM1_META1p4915 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); Function of strongly homologous gene; enzyme. | 0.731 |
ACS40459.1 | thiE | MexAM1_META1p2693 | MexAM1_META1p0427 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.605 |
ACS40459.1 | thiE-2 | MexAM1_META1p2693 | MexAM1_META1p4916 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.605 |
ACS40459.1 | thiG | MexAM1_META1p2693 | MexAM1_META1p0428 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.861 |
ACS40459.1 | thiS | MexAM1_META1p2693 | MexAM1_META1p0429 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thiamin biosynthesis proteinsulfur carrier) ThiS; Function of strongly homologous gene; factor. | 0.939 |
ACS42507.1 | ACS40154.1 | MexAM1_META1p4898 | MexAM1_META1p2371 | Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Thiamine-phosphate pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.506 |
ACS42507.1 | ACS40459.1 | MexAM1_META1p4898 | MexAM1_META1p2693 | Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.633 |
ACS42507.1 | moeB | MexAM1_META1p4898 | MexAM1_META1p1526 | Putative transcriptional activator (TenA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Molybdopterin synthase sulfurylase; Function of strongly homologous gene; enzyme. | 0.635 |