STRINGSTRING
ACS38440.1 ACS38440.1 ACS39430.1 ACS39430.1 ACS40365.1 ACS40365.1 ACS42492.1 ACS42492.1 dnaN dnaN ACS42520.1 ACS42520.1 ACS40102.1 ACS40102.1 ACS42467.1 ACS42467.1 ACS40986.1 ACS40986.1 hemF hemF ACS38359.1 ACS38359.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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Textmining
[Homology]
Score
ACS38440.1Function of strongly homologous gene; enzyme. (373 aa)    
Predicted Functional Partners:
ACS39430.1
Putative ATP-dependent exodeoxyribonuclease (Subunit A)/helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily.
  
 
 0.755
ACS40365.1
UvrD/REP helicase; Function of strongly homologous gene; enzyme; Belongs to the helicase family. UvrD subfamily.
  
 
 0.755
ACS42492.1
Putative helicase-exonuclease type V protein family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily.
  
 
 0.755
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.738
ACS42520.1
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.704
ACS40102.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.695
ACS42467.1
Conserved hypothetical protein with putative domain: trypsin-like serine protease; Homologs of previously reported genes of unknown function.
  
     0.695
ACS40986.1
Hypothetical protein; No homology to any previously reported sequences.
  
     0.672
hemF
Coproporphyrinogen III oxidase, aerobic (Coproporphyrinogenase) (Coprogen oxidase); Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
       0.666
ACS38359.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.660
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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