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amn amn apt apt ade ade xapA xapA purB purB ACS39227.1 ACS39227.1 adk adk mazG mazG surE surE ACS40224.1 ACS40224.1 ACS38477.1 ACS38477.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (495 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.924
ade
Adenine deaminase (Adenase) (Adenine aminase); Function of strongly homologous gene; enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.914
xapA
Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.909
purB
Adenylosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 
  0.900
ACS39227.1
Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family.
     
  0.900
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
surE
5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.900
ACS40224.1
Putative pilus assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the bacterial secretin family.
  
    0.587
ACS38477.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.570
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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