node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38483.1 | ACS38484.1 | MexAM1_META1p0542 | MexAM1_META1p0543 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | Hypothetical protein, putative chaperone-like protein; No homology to any previously reported sequences. | 0.535 |
ACS38483.1 | ACS38485.1 | MexAM1_META1p0542 | MexAM1_META1p0544 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | Hypothetical protein, lamin-like protein; No homology to any previously reported sequences. | 0.482 |
ACS38483.1 | ACS39663.1 | MexAM1_META1p0542 | MexAM1_META1p1821 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.434 |
ACS38483.1 | gyrB | MexAM1_META1p0542 | MexAM1_META1p2546 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.532 |
ACS38483.1 | parE | MexAM1_META1p0542 | MexAM1_META1p3331 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.532 |
ACS38483.1 | polA | MexAM1_META1p0542 | MexAM1_META1p2436 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.606 |
ACS38483.1 | recA | MexAM1_META1p0542 | MexAM1_META1p2721 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.401 |
ACS38483.1 | recQ | MexAM1_META1p0542 | MexAM1_META1p0005 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.590 |
ACS38483.1 | sbcC | MexAM1_META1p0542 | MexAM1_META1p0195 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | Nuclease sbcCD subunit C; Function of strongly homologous gene; enzyme. | 0.410 |
ACS38483.1 | topA | MexAM1_META1p0542 | MexAM1_META1p3523 | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.570 |
ACS38484.1 | ACS38483.1 | MexAM1_META1p0543 | MexAM1_META1p0542 | Hypothetical protein, putative chaperone-like protein; No homology to any previously reported sequences. | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | 0.535 |
ACS38484.1 | ACS38485.1 | MexAM1_META1p0543 | MexAM1_META1p0544 | Hypothetical protein, putative chaperone-like protein; No homology to any previously reported sequences. | Hypothetical protein, lamin-like protein; No homology to any previously reported sequences. | 0.723 |
ACS38485.1 | ACS38483.1 | MexAM1_META1p0544 | MexAM1_META1p0542 | Hypothetical protein, lamin-like protein; No homology to any previously reported sequences. | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | 0.482 |
ACS38485.1 | ACS38484.1 | MexAM1_META1p0544 | MexAM1_META1p0543 | Hypothetical protein, lamin-like protein; No homology to any previously reported sequences. | Hypothetical protein, putative chaperone-like protein; No homology to any previously reported sequences. | 0.723 |
ACS39663.1 | ACS38483.1 | MexAM1_META1p1821 | MexAM1_META1p0542 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative crescentin (creS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. | 0.434 |
ACS39663.1 | gyrB | MexAM1_META1p1821 | MexAM1_META1p2546 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.431 |
ACS39663.1 | parE | MexAM1_META1p1821 | MexAM1_META1p3331 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.431 |
ACS39663.1 | polA | MexAM1_META1p1821 | MexAM1_META1p2436 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.711 |
ACS39663.1 | recA | MexAM1_META1p1821 | MexAM1_META1p2721 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.681 |
ACS39663.1 | recQ | MexAM1_META1p1821 | MexAM1_META1p0005 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.526 |