node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38209.1 | ACS38322.1 | MexAM1_META1p0249 | MexAM1_META1p0374 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.775 |
ACS38209.1 | ACS39663.1 | MexAM1_META1p0249 | MexAM1_META1p1821 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
ACS38209.1 | bioA | MexAM1_META1p0249 | MexAM1_META1p0619 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.622 |
ACS38209.1 | bioB | MexAM1_META1p0249 | MexAM1_META1p4394 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.742 |
ACS38209.1 | bioD | MexAM1_META1p0249 | MexAM1_META1p2335 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.885 |
ACS38209.1 | gcvP | MexAM1_META1p0249 | MexAM1_META1p0620 | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.409 |
ACS38322.1 | ACS38209.1 | MexAM1_META1p0374 | MexAM1_META1p0249 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.775 |
ACS38322.1 | ACS39663.1 | MexAM1_META1p0374 | MexAM1_META1p1821 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.621 |
ACS38322.1 | bioA | MexAM1_META1p0374 | MexAM1_META1p0619 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.631 |
ACS38322.1 | bioB | MexAM1_META1p0374 | MexAM1_META1p4394 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.742 |
ACS38322.1 | bioD | MexAM1_META1p0374 | MexAM1_META1p2335 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.887 |
ACS38322.1 | gcvP | MexAM1_META1p0374 | MexAM1_META1p0620 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.938 |
ACS38322.1 | hemA | MexAM1_META1p0374 | MexAM1_META1p1968 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |
ACS38322.1 | hemA-2 | MexAM1_META1p0374 | MexAM1_META1p5261 | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |
ACS39663.1 | ACS38209.1 | MexAM1_META1p1821 | MexAM1_META1p0249 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 5-aminolevulinate synthase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
ACS39663.1 | ACS38322.1 | MexAM1_META1p1821 | MexAM1_META1p0374 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.621 |
ACS39663.1 | bioA | MexAM1_META1p1821 | MexAM1_META1p0619 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.477 |
ACS39663.1 | bioF | MexAM1_META1p1821 | MexAM1_META1p0624 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 7-keto-8-aminopelargonic acid synthetase (8-amino-7-oxononanoate synthase; Function of strongly homologous gene; enzyme. | 0.644 |
ACS39663.1 | gcvP | MexAM1_META1p1821 | MexAM1_META1p0620 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.562 |
ACS39663.1 | hemA | MexAM1_META1p1821 | MexAM1_META1p1968 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.562 |