Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS38751.1 | ftfL | MexAM1_META1p0830 | MexAM1_META1p0329 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | 0.466 |
| ACS38751.1 | gcvT | MexAM1_META1p0830 | MexAM1_META1p0622 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme. | 0.962 |
| ACS38751.1 | glyA | MexAM1_META1p0830 | MexAM1_META1p3384 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.948 |
| ACS38751.1 | purH | MexAM1_META1p0830 | MexAM1_META1p2535 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.722 |
| ACS38751.1 | purN | MexAM1_META1p0830 | MexAM1_META1p2044 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.967 |
| ACS38751.1 | thyA | MexAM1_META1p0830 | MexAM1_META1p2853 | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.816 |
| ftfL | ACS38751.1 | MexAM1_META1p0329 | MexAM1_META1p0830 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Putative Formyl transferase (fmt-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.466 |
| ftfL | gcvH | MexAM1_META1p0329 | MexAM1_META1p0621 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.450 |
| ftfL | gcvP | MexAM1_META1p0329 | MexAM1_META1p0620 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.776 |
| ftfL | gcvT | MexAM1_META1p0329 | MexAM1_META1p0622 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme. | 0.958 |
| ftfL | glyA | MexAM1_META1p0329 | MexAM1_META1p3384 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.988 |
| ftfL | purH | MexAM1_META1p0329 | MexAM1_META1p2535 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Bifunctional: IMP cyclohydrolase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.992 |
| ftfL | purN | MexAM1_META1p0329 | MexAM1_META1p2044 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.982 |
| ftfL | thyA | MexAM1_META1p0329 | MexAM1_META1p2853 | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.529 |
| gcvH | ftfL | MexAM1_META1p0621 | MexAM1_META1p0329 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. | 0.450 |
| gcvH | gcvP | MexAM1_META1p0621 | MexAM1_META1p0620 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvH | gcvT | MexAM1_META1p0621 | MexAM1_META1p0622 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme. | 0.999 |
| gcvH | glyA | MexAM1_META1p0621 | MexAM1_META1p3384 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.991 |
| gcvH | lpd | MexAM1_META1p0621 | MexAM1_META1p1542 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.978 |
| gcvH | lpd-2 | MexAM1_META1p0621 | MexAM1_META1p2990 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase, E3 Component of Pyruvate dehydrogenase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.975 |
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