node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38063.1 | ACS38598.1 | MexAM1_META1p0096 | MexAM1_META1p0669 | Putative methyltransferase, putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.482 |
ACS38063.1 | ACS41084.1 | MexAM1_META1p0096 | MexAM1_META1p3347 | Putative methyltransferase, putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.812 |
ACS38598.1 | ACS38063.1 | MexAM1_META1p0669 | MexAM1_META1p0096 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative methyltransferase, putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.482 |
ACS38598.1 | ACS38599.1 | MexAM1_META1p0669 | MexAM1_META1p0670 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative L-asparaginase (ansA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.675 |
ACS38598.1 | ACS41084.1 | MexAM1_META1p0669 | MexAM1_META1p3347 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.507 |
ACS38598.1 | ACS41269.1 | MexAM1_META1p0669 | MexAM1_META1p3534 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.493 |
ACS38598.1 | ACS41871.1 | MexAM1_META1p0669 | MexAM1_META1p4234 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein with putative pseudouridine synthase-like domain; Homologs of previously reported genes of unknown function; Belongs to the pseudouridine synthase RsuA family. | 0.455 |
ACS38598.1 | dnaJ | MexAM1_META1p0669 | MexAM1_META1p3165 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Heat shock protein (Hsp40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...] | 0.454 |
ACS38598.1 | gshA | MexAM1_META1p0669 | MexAM1_META1p0671 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Gamma-glutamylcysteine synthetase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | 0.475 |
ACS38598.1 | gshB | MexAM1_META1p0669 | MexAM1_META1p0712 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Glutathione synthetase; Function of strongly homologous gene; enzyme; Belongs to the prokaryotic GSH synthase family. | 0.444 |
ACS38598.1 | nadD | MexAM1_META1p0669 | MexAM1_META1p3073 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.469 |
ACS38598.1 | prmA | MexAM1_META1p0669 | MexAM1_META1p4925 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.851 |
ACS38599.1 | ACS38598.1 | MexAM1_META1p0670 | MexAM1_META1p0669 | Putative L-asparaginase (ansA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.675 |
ACS38599.1 | gshA | MexAM1_META1p0670 | MexAM1_META1p0671 | Putative L-asparaginase (ansA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Gamma-glutamylcysteine synthetase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | 0.451 |
ACS41084.1 | ACS38063.1 | MexAM1_META1p3347 | MexAM1_META1p0096 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative methyltransferase, putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.812 |
ACS41084.1 | ACS38598.1 | MexAM1_META1p3347 | MexAM1_META1p0669 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.507 |
ACS41269.1 | ACS38598.1 | MexAM1_META1p3534 | MexAM1_META1p0669 | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.493 |
ACS41871.1 | ACS38598.1 | MexAM1_META1p4234 | MexAM1_META1p0669 | Conserved hypothetical protein with putative pseudouridine synthase-like domain; Homologs of previously reported genes of unknown function; Belongs to the pseudouridine synthase RsuA family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.455 |
dnaJ | ACS38598.1 | MexAM1_META1p3165 | MexAM1_META1p0669 | Heat shock protein (Hsp40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...] | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.454 |
dnaJ | prmA | MexAM1_META1p3165 | MexAM1_META1p4925 | Heat shock protein (Hsp40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...] | Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.777 |