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frc-2 frc-2 ACS38885.1 ACS38885.1 glcF glcF hyi hyi doc doc ACS38896.1 ACS38896.1 ACS38893.1 ACS38893.1 mcl mcl ACS39663.1 ACS39663.1 ACS41189.1 ACS41189.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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frc-2formyl-CoA transferase, NAD(P)-binding; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily. (429 aa)    
Predicted Functional Partners:
ACS38885.1
Putative oxalyl-CoA decarboxylase (oxc, yfdU); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TPP enzyme family.
 
 
 0.784
glcF
Glycolate oxidase iron-sulfur subunit; Function of strongly homologous gene; carrier.
   
  
 0.691
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the hyi family.
      
 0.689
doc
Death-on-curing family protein; Function of strongly homologous gene; extrachromosomal origin.
      
 0.660
ACS38896.1
Transcriptional regulator, GntR family; Function of strongly homologous gene; regulator.
 
     0.574
ACS38893.1
Hypothetical protein; No homology to any previously reported sequences.
       0.486
mcl
malyl-CoA lyase/beta-methylmalyl-CoA lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.478
ACS39663.1
Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.473
ACS41189.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.422
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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