node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38905.1 | ACS38906.1 | MexAM1_META1p1011 | MexAM1_META1p1012 | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.841 |
ACS38905.1 | exsB | MexAM1_META1p1011 | MexAM1_META1p1010 | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.757 |
ACS38905.1 | ptpS | MexAM1_META1p1011 | MexAM1_META1p1009 | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.757 |
ACS38906.1 | ACS38905.1 | MexAM1_META1p1012 | MexAM1_META1p1011 | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.841 |
ACS38906.1 | exsB | MexAM1_META1p1012 | MexAM1_META1p1010 | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.545 |
ACS38906.1 | ptpS | MexAM1_META1p1012 | MexAM1_META1p1009 | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.545 |
exsB | ACS38905.1 | MexAM1_META1p1010 | MexAM1_META1p1011 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.757 |
exsB | ACS38906.1 | MexAM1_META1p1010 | MexAM1_META1p1012 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.545 |
exsB | ptpS | MexAM1_META1p1010 | MexAM1_META1p1009 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.988 |
exsB | queA | MexAM1_META1p1010 | MexAM1_META1p3283 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.456 |
exsB | queE | MexAM1_META1p1010 | MexAM1_META1p1004 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
exsB | queF | MexAM1_META1p1010 | MexAM1_META1p2983 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.994 |
exsB | ribAB | MexAM1_META1p1010 | MexAM1_META1p3198 | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.425 |
ptpS | ACS38905.1 | MexAM1_META1p1009 | MexAM1_META1p1011 | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative LmbE-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.757 |
ptpS | ACS38906.1 | MexAM1_META1p1009 | MexAM1_META1p1012 | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.545 |
ptpS | exsB | MexAM1_META1p1009 | MexAM1_META1p1010 | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.988 |
ptpS | queE | MexAM1_META1p1009 | MexAM1_META1p1004 | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.994 |
ptpS | queF | MexAM1_META1p1009 | MexAM1_META1p2983 | Putative 6-pyruvol tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.904 |
queA | exsB | MexAM1_META1p3283 | MexAM1_META1p1010 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Putative regulator, ATP-binding; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.456 |
queA | queF | MexAM1_META1p3283 | MexAM1_META1p2983 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.645 |