node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cmk | ffh | MexAM1_META1p2119 | MexAM1_META1p0477 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | 0.854 |
cmk | ftsZ | MexAM1_META1p2119 | MexAM1_META1p3154 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.450 |
cmk | minC-2 | MexAM1_META1p2119 | MexAM1_META1p1052 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.499 |
cmk | tgt | MexAM1_META1p2119 | MexAM1_META1p3285 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...] | 0.516 |
ffh | cmk | MexAM1_META1p0477 | MexAM1_META1p2119 | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | 0.854 |
ffh | ftsZ | MexAM1_META1p0477 | MexAM1_META1p3154 | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.660 |
ffh | minC-2 | MexAM1_META1p0477 | MexAM1_META1p1052 | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.598 |
ftsE | ftsK-2 | MexAM1_META1p3067 | MexAM1_META1p4424 | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | 0.728 |
ftsE | ftsZ | MexAM1_META1p3067 | MexAM1_META1p3154 | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.534 |
ftsE | mauL | MexAM1_META1p3067 | MexAM1_META1p2777 | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | Methylamine utilization protein mauL; Probably involved in TTQ prosthetic group biosynthesis. | 0.513 |
ftsE | minC-2 | MexAM1_META1p3067 | MexAM1_META1p1052 | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.741 |
ftsE | sbcD | MexAM1_META1p3067 | MexAM1_META1p0194 | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.449 |
ftsK-2 | ftsE | MexAM1_META1p4424 | MexAM1_META1p3067 | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | 0.728 |
ftsK-2 | ftsZ | MexAM1_META1p4424 | MexAM1_META1p3154 | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.696 |
ftsK-2 | minC-2 | MexAM1_META1p4424 | MexAM1_META1p1052 | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.704 |
ftsK-2 | sbcD | MexAM1_META1p4424 | MexAM1_META1p0194 | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.440 |
ftsK-2 | tgt | MexAM1_META1p4424 | MexAM1_META1p3285 | Cell division protein; Function of strongly homologous gene; cell process; Belongs to the FtsK/SpoIIIE/SftA family. | Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...] | 0.616 |
ftsZ | cmk | MexAM1_META1p3154 | MexAM1_META1p2119 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | 0.450 |
ftsZ | ffh | MexAM1_META1p3154 | MexAM1_META1p0477 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Signal recognition particle protein, GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual [...] | 0.660 |
ftsZ | ftsE | MexAM1_META1p3154 | MexAM1_META1p3067 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. | 0.534 |