node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40059.1 | ACS40539.1 | MexAM1_META1p2273 | MexAM1_META1p2781 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative antioxidant enzyme, Tpx-related thiol peroxidase domain; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.542 |
ACS40059.1 | bamD | MexAM1_META1p2273 | MexAM1_META1p3156 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.744 |
ACS40059.1 | minE | MexAM1_META1p2273 | MexAM1_META1p1054 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.787 |
ACS40059.1 | mntR | MexAM1_META1p2273 | MexAM1_META1p3854 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | DNA-binding transcriptional regulator of mntH; Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.551 |
ACS40059.1 | phoU | MexAM1_META1p2273 | MexAM1_META1p5168 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Negative regulator of PhoR/PhoB two-component regulator; Plays a role in the regulation of phosphate uptake. | 0.575 |
ACS40059.1 | rpoN | MexAM1_META1p2273 | MexAM1_META1p2466 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.698 |
ACS40059.1 | yliG | MexAM1_META1p2273 | MexAM1_META1p4287 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.776 |
ACS40539.1 | ACS40059.1 | MexAM1_META1p2781 | MexAM1_META1p2273 | Putative antioxidant enzyme, Tpx-related thiol peroxidase domain; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.542 |
ACS40539.1 | minE | MexAM1_META1p2781 | MexAM1_META1p1054 | Putative antioxidant enzyme, Tpx-related thiol peroxidase domain; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.593 |
ACS40539.1 | mntR | MexAM1_META1p2781 | MexAM1_META1p3854 | Putative antioxidant enzyme, Tpx-related thiol peroxidase domain; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | DNA-binding transcriptional regulator of mntH; Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.610 |
bamD | ACS40059.1 | MexAM1_META1p3156 | MexAM1_META1p2273 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.744 |
bamD | minE | MexAM1_META1p3156 | MexAM1_META1p1054 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.605 |
bamD | rpoN | MexAM1_META1p3156 | MexAM1_META1p2466 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.510 |
minC | minD | MexAM1_META1p1048 | MexAM1_META1p1053 | Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.990 |
minC | minE | MexAM1_META1p1048 | MexAM1_META1p1054 | Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.843 |
minC-2 | minD | MexAM1_META1p1052 | MexAM1_META1p1053 | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |
minC-2 | minE | MexAM1_META1p1052 | MexAM1_META1p1054 | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.957 |
minD | minC | MexAM1_META1p1053 | MexAM1_META1p1048 | Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.990 |
minD | minC-2 | MexAM1_META1p1053 | MexAM1_META1p1052 | Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.997 |
minD | minE | MexAM1_META1p1053 | MexAM1_META1p1054 | Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.998 |