STRINGSTRING
minE minE minD minD minC-2 minC-2 minC minC ACS40059.1 ACS40059.1 phoU phoU bamD bamD ACS40539.1 ACS40539.1 rpoN rpoN yliG yliG mntR mntR
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (95 aa)    
Predicted Functional Partners:
minD
Membrane ATPase of the MinC-MinD-MinE system; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.998
minC-2
Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.957
minC
Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.843
ACS40059.1
Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family.
   
    0.787
phoU
Negative regulator of PhoR/PhoB two-component regulator; Plays a role in the regulation of phosphate uptake.
  
    0.613
bamD
Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.605
ACS40539.1
Putative antioxidant enzyme, Tpx-related thiol peroxidase domain; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
    0.593
rpoN
Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
    0.584
yliG
Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
    0.547
mntR
DNA-binding transcriptional regulator of mntH; Function of homologous gene experimentally demonstrated in an other organism; regulator.
   
    0.516
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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