STRINGSTRING
icuA icuA icuB icuB ACS38697.1 ACS38697.1 ACS39372.1 ACS39372.1 tolA tolA tolB tolB ACS40877.1 ACS40877.1 ACS40027.1 ACS40027.1 ACS41782.1 ACS41782.1 ACS41783.1 ACS41783.1 metH metH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icuAConserved hypothetical exported protein, putative outer membrane receptor protein; Homologs of previously reported genes of unknown function. (704 aa)    
Predicted Functional Partners:
icuB
Hypothetical protein; No homology to any previously reported sequences.
 
   
 0.946
ACS38697.1
TonB family protein precursor.
   
 
 0.698
ACS39372.1
Putative TonB family C-terminal domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 
 0.698
tolA
Colicin import membrane protein; Function of strongly homologous gene; membrane component.
   
 
 0.698
tolB
Protein tolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 
 0.587
ACS40877.1
Putative TonB-dependent receptor protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
   
 0.560
ACS40027.1
Putative TonB-dependent receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
  
   
 0.514
ACS41782.1
tonB-dependent siderophore receptor protein; Function of strongly homologous gene; putative receptor.
  
   
 0.490
ACS41783.1
Putative FecR, iron siderophore sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   
 0.488
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.484
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (24%) [HD]