node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38512.1 | ACS39052.1 | MexAM1_META1p0582 | MexAM1_META1p1183 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.403 |
ACS39051.1 | ACS39052.1 | MexAM1_META1p1182 | MexAM1_META1p1183 | Putative short-chain dehydrogenase/reductase SDR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.484 |
ACS39051.1 | ACS39053.1 | MexAM1_META1p1182 | MexAM1_META1p1184 | Putative short-chain dehydrogenase/reductase SDR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative zink-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.415 |
ACS39052.1 | ACS38512.1 | MexAM1_META1p1183 | MexAM1_META1p0582 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.403 |
ACS39052.1 | ACS39051.1 | MexAM1_META1p1183 | MexAM1_META1p1182 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative short-chain dehydrogenase/reductase SDR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.484 |
ACS39052.1 | ACS39053.1 | MexAM1_META1p1183 | MexAM1_META1p1184 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative zink-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.642 |
ACS39052.1 | ACS39074.1 | MexAM1_META1p1183 | MexAM1_META1p1209 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Major Facilitator Family (MFS) transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.430 |
ACS39052.1 | nadE | MexAM1_META1p1183 | MexAM1_META1p4425 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD(+) synthase (glutamine-hydrolyzing) with a nitrilase-like domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.570 |
ACS39052.1 | nnrE | MexAM1_META1p1183 | MexAM1_META1p2375 | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.532 |
ACS39053.1 | ACS39051.1 | MexAM1_META1p1184 | MexAM1_META1p1182 | Putative zink-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative short-chain dehydrogenase/reductase SDR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.415 |
ACS39053.1 | ACS39052.1 | MexAM1_META1p1184 | MexAM1_META1p1183 | Putative zink-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.642 |
ACS39074.1 | ACS39052.1 | MexAM1_META1p1209 | MexAM1_META1p1183 | Putative Major Facilitator Family (MFS) transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.430 |
nadE | ACS39052.1 | MexAM1_META1p4425 | MexAM1_META1p1183 | NAD(+) synthase (glutamine-hydrolyzing) with a nitrilase-like domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.570 |
nadE | nnrE | MexAM1_META1p4425 | MexAM1_META1p2375 | NAD(+) synthase (glutamine-hydrolyzing) with a nitrilase-like domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.510 |
nnrE | ACS39052.1 | MexAM1_META1p2375 | MexAM1_META1p1183 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Putative Isochorismatase hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.532 |
nnrE | nadE | MexAM1_META1p2375 | MexAM1_META1p4425 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | NAD(+) synthase (glutamine-hydrolyzing) with a nitrilase-like domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.510 |