STRINGSTRING
sugE sugE emrE emrE ACS39372.1 ACS39372.1 ampC ampC dinB dinB ACS39146.1 ACS39146.1 pbpC pbpC parE parE trpB trpB trpA trpA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
sugEMultidrug efflux system protein; Function of homologous gene experimentally demonstrated in an other organism; transporter. (106 aa)    
Predicted Functional Partners:
emrE
Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.
 
  
 0.836
ACS39372.1
Putative TonB family C-terminal domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.699
ampC
beta-lactamase/D-ala carboxypeptidase; Function of strongly homologous gene; enzyme.
   
  
 0.669
dinB
DNA polymerase IV (Pol IV); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
      
 0.660
ACS39146.1
Conserved hypothetical protein (large extracellular alpha-helical protein); Homologs of previously reported genes of unknown function.
  
    0.502
pbpC
Penicillin binding protein; Function of strongly homologous gene; enzyme.
       0.486
parE
DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
      
 0.456
trpB
Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.449
trpA
Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.405
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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