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cycK cycK cycL cycL cycH cycH ccmG ccmG cycJ cycJ ccmC ccmC ccmB ccmB ccmA ccmA ACS40412.1 ACS40412.1 ACS39104.1 ACS39104.1 ACS39547.1 ACS39547.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cycKCytochrome c-type biogenesis protein CycK; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (666 aa)    
Predicted Functional Partners:
cycL
Cytochrome c-type biogenesis protein CycL precursor; Possible subunit of a heme lyase.
  
 0.998
cycH
Cytochrome c-type biogenesis protein CycH; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 
 0.981
ccmG
Periplasmic protein thiol:disulfide oxidoreductase, cytochrome c-type biogenesis; Function of strongly homologous gene; enzyme.
 
  
 0.971
cycJ
Cytochrome c-type biogenesis protein CycJ; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.963
ccmC
Heme exporter protein, cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.951
ccmB
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.948
ccmA
Heme export protein, cytochrome C-type biogenesis ccmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.818
ACS40412.1
Redoxin domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.572
ACS39104.1
Thioredoxin-related; Function of strongly homologous gene; enzyme.
  
  
 0.515
ACS39547.1
Thioredoxin-related; Function of strongly homologous gene; putative enzyme.
  
  
 0.515
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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