STRINGSTRING
cycJ cycJ ccmC ccmC cycK cycK cycL cycL ccmB ccmB ccmG ccmG cycH cycH ccmA ccmA petA petA ACS39160.1 ACS39160.1 ACS39154.1 ACS39154.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cycJCytochrome c-type biogenesis protein CycJ; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (177 aa)    
Predicted Functional Partners:
ccmC
Heme exporter protein, cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 
 0.989
cycK
Cytochrome c-type biogenesis protein CycK; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.963
cycL
Cytochrome c-type biogenesis protein CycL precursor; Possible subunit of a heme lyase.
 
  
 0.946
ccmB
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.938
ccmG
Periplasmic protein thiol:disulfide oxidoreductase, cytochrome c-type biogenesis; Function of strongly homologous gene; enzyme.
 
  
 0.900
cycH
Cytochrome c-type biogenesis protein CycH; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
  
 0.887
ccmA
Heme export protein, cytochrome C-type biogenesis ccmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 
 0.881
petA
Ubiquinol-cytochrome c reductase complex, iron-sulfur subunit (Rieske iron-sulfur protein); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
   
 0.530
ACS39160.1
Integral membrane sensor signal transduction histidine kinase precursor; Function of strongly homologous gene; receptor.
 
     0.480
ACS39154.1
Putative high-affinity nickel-transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.425
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.