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cycH cycH cycK cycK cycL cycL ccmG ccmG cycJ cycJ ccmB ccmB ccmC ccmC ccmA ccmA ACS39160.1 ACS39160.1 ACS38021.1 ACS38021.1 ACS39644.1 ACS39644.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cycHCytochrome c-type biogenesis protein CycH; Function of homologous gene experimentally demonstrated in an other organism; factor. (527 aa)    
Predicted Functional Partners:
cycK
Cytochrome c-type biogenesis protein CycK; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.981
cycL
Cytochrome c-type biogenesis protein CycL precursor; Possible subunit of a heme lyase.
 
  
 0.946
ccmG
Periplasmic protein thiol:disulfide oxidoreductase, cytochrome c-type biogenesis; Function of strongly homologous gene; enzyme.
 
  
 0.917
cycJ
Cytochrome c-type biogenesis protein CycJ; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.887
ccmB
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
   
 0.804
ccmC
Heme exporter protein, cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.733
ccmA
Heme export protein, cytochrome C-type biogenesis ccmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.711
ACS39160.1
Integral membrane sensor signal transduction histidine kinase precursor; Function of strongly homologous gene; receptor.
       0.532
ACS38021.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.516
ACS39644.1
Transglutaminase family protein cysteine peptidase precursor; Function of strongly homologous gene; enzyme.
  
     0.476
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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