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cobI cobI cobJ cobJ cobG cobG cobH cobH cobL cobL cobM cobM cobK cobK ACS39192.1 ACS39192.1 cysG cysG cobQ cobQ ACS38723.1 ACS38723.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cobIPrecorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. (265 aa)    
Predicted Functional Partners:
cobJ
Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.999
cobG
precorrin-3B synthase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.994
cobH
Precorrin-8X methylmutase (Precorrin isomerase) (HBA synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.992
cobL
Precorrin-6Y C5,15-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.977
cobM
Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
 
  
 0.969
cobK
Precorrin-6A reductase (Precorrin-6X reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.967
ACS39192.1
Putative cobaltochelatase, CobN subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.959
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
 0.956
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.909
ACS38723.1
Putative cobalamin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.895
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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