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cobH cobH cobJ cobJ cobL cobL cobB cobB cobI cobI cobG cobG cobQ cobQ cobM cobM cobK cobK ACS39192.1 ACS39192.1 cobF cobF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobHPrecorrin-8X methylmutase (Precorrin isomerase) (HBA synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (210 aa)    
Predicted Functional Partners:
cobJ
Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.999
cobL
Precorrin-6Y C5,15-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.998
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.994
cobI
Precorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
 
  
 0.992
cobG
precorrin-3B synthase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.982
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.978
cobM
Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
 
  
 0.973
cobK
Precorrin-6A reductase (Precorrin-6X reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.971
ACS39192.1
Putative cobaltochelatase, CobN subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.962
cobF
Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.
 
  
 0.962
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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