STRINGSTRING
cobG cobG cobI cobI cobJ cobJ cobH cobH ACS39192.1 ACS39192.1 ACS39195.1 ACS39195.1 cysG cysG cobF cobF cysJ cysJ ACS42546.1 ACS42546.1 cysN cysN
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobGprecorrin-3B synthase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (428 aa)    
Predicted Functional Partners:
cobI
Precorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
 
 
 0.994
cobJ
Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.993
cobH
Precorrin-8X methylmutase (Precorrin isomerase) (HBA synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.982
ACS39192.1
Putative cobaltochelatase, CobN subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 0.944
ACS39195.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.928
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.907
cobF
Precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.
 
  
 0.900
cysJ
Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
  
 
 0.895
ACS42546.1
Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.881
cysN
ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.848
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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