node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39227.1 | deoA | MexAM1_META1p1365 | MexAM1_META1p3168 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.924 |
ACS39227.1 | guaA | MexAM1_META1p1365 | MexAM1_META1p3135 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.919 |
ACS39227.1 | mazG | MexAM1_META1p1365 | MexAM1_META1p4291 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Nucleoside triphosphate pyrophosphohydrolase MazG; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
ACS39227.1 | pyrF | MexAM1_META1p1365 | MexAM1_META1p1411 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.901 |
ACS39227.1 | pyrH | MexAM1_META1p1365 | MexAM1_META1p2059 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
ACS39227.1 | surE | MexAM1_META1p1365 | MexAM1_META1p4626 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
ACS39227.1 | upp | MexAM1_META1p1365 | MexAM1_META1p1439 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.901 |
ACS39227.1 | xapA | MexAM1_META1p1365 | MexAM1_META1p3170 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.910 |
ACS39498.1 | deoA | MexAM1_META1p1649 | MexAM1_META1p3168 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.926 |
ACS39498.1 | rutF | MexAM1_META1p1649 | MexAM1_META1p1660 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | upp | MexAM1_META1p1649 | MexAM1_META1p1439 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.945 |
ACS39498.1 | xapA | MexAM1_META1p1649 | MexAM1_META1p3170 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
deoA | ACS39227.1 | MexAM1_META1p3168 | MexAM1_META1p1365 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 0.924 |
deoA | ACS39498.1 | MexAM1_META1p3168 | MexAM1_META1p1649 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.926 |
deoA | guaA | MexAM1_META1p3168 | MexAM1_META1p3135 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.462 |
deoA | rutF | MexAM1_META1p3168 | MexAM1_META1p1660 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
deoA | surE | MexAM1_META1p3168 | MexAM1_META1p4626 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.934 |
deoA | upp | MexAM1_META1p3168 | MexAM1_META1p1439 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.956 |
deoA | xapA | MexAM1_META1p3168 | MexAM1_META1p3170 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.991 |
guaA | ACS39227.1 | MexAM1_META1p3135 | MexAM1_META1p1365 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 0.919 |