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poxB poxB ilvH ilvH dme dme leuA leuA pdhB pdhB aldA aldA pyk pyk pyk-2 pyk-2 pdhA pdhA ppdK ppdK ackA ackA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
poxBpoxB; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (577 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase III, small subunit; Function of strongly homologous gene; enzyme.
 
 0.989
dme
NAD-dependent malic enzyme; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.
  
 
 0.952
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.944
pdhB
Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.932
aldA
Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.917
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
  
 0.914
pyk-2
Pyruvate kinase; Function of strongly homologous gene; enzyme.
  
 0.914
pdhA
Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.914
ppdK
Pyruvate phosphate dikinase (Pyruvate, orthophosphate dikinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PEP-utilizing enzyme family.
  
 
 0.911
ackA
Putative acetate kinase (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.904
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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