node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39331.1 | ACS40836.1 | MexAM1_META1p1469 | MexAM1_META1p3089 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved hypothetical protein with putative globin-like domain; Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.847 |
ACS39331.1 | ACS41806.1 | MexAM1_META1p1469 | MexAM1_META1p4154 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.851 |
ACS39331.1 | cmk | MexAM1_META1p1469 | MexAM1_META1p2119 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | 0.605 |
ACS39331.1 | murF | MexAM1_META1p1469 | MexAM1_META1p5086 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.744 |
ACS39331.1 | pdxY | MexAM1_META1p1469 | MexAM1_META1p2863 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyridoxal kinase 2/pyridoxine kinase; Function of strongly homologous gene; enzyme; Belongs to the pyridoxine kinase family. | 0.832 |
ACS39331.1 | proC | MexAM1_META1p1469 | MexAM1_META1p4140 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.793 |
ACS39331.1 | rlmN | MexAM1_META1p1469 | MexAM1_META1p1534 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative Fe-S containing enzyme (yfgB); Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.685 |
ACS39331.1 | rplX | MexAM1_META1p1469 | MexAM1_META1p2181 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.720 |
ACS39331.1 | rpmC | MexAM1_META1p1469 | MexAM1_META1p2161 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 50S ribosomal subunit protein L29; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uL29 family. | 0.735 |
ACS39331.1 | rpmJ | MexAM1_META1p1469 | MexAM1_META1p2938 | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 50S ribosomal protein L36; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bL36 family. | 0.710 |
ACS40836.1 | ACS39331.1 | MexAM1_META1p3089 | MexAM1_META1p1469 | Conserved hypothetical protein with putative globin-like domain; Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.847 |
ACS41806.1 | ACS39331.1 | MexAM1_META1p4154 | MexAM1_META1p1469 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.851 |
ACS41806.1 | proC | MexAM1_META1p4154 | MexAM1_META1p4140 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.456 |
cmk | ACS39331.1 | MexAM1_META1p2119 | MexAM1_META1p1469 | Cytidine monophosphate (CMP) kinase; Function of strongly homologous gene; enzyme. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.605 |
murF | ACS39331.1 | MexAM1_META1p5086 | MexAM1_META1p1469 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.744 |
pdxY | ACS39331.1 | MexAM1_META1p2863 | MexAM1_META1p1469 | Pyridoxal kinase 2/pyridoxine kinase; Function of strongly homologous gene; enzyme; Belongs to the pyridoxine kinase family. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.832 |
proC | ACS39331.1 | MexAM1_META1p4140 | MexAM1_META1p1469 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.793 |
proC | ACS41806.1 | MexAM1_META1p4140 | MexAM1_META1p4154 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.456 |
rlmN | ACS39331.1 | MexAM1_META1p1534 | MexAM1_META1p1469 | Putative Fe-S containing enzyme (yfgB); Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.685 |
rplX | ACS39331.1 | MexAM1_META1p2181 | MexAM1_META1p1469 | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | Putative enzyme with PLP-binding domain, putative alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.720 |