STRINGSTRING
ACS39340.1 ACS39340.1 dnaN dnaN ACS42709.1 ACS42709.1 holB holB dnaE dnaE dnaX dnaX ACS38179.1 ACS38179.1 dnaQ dnaQ ACS39341.1 ACS39341.1 ACS42491.1 ACS42491.1 dnaE-2 dnaE-2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACS39340.1Putative DNA polymerase III, delta subunit, holA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (343 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.985
ACS42709.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.985
holB
DNA polymerase III, delta prime subunit; Function of strongly homologous gene; putative enzyme.
 
 
 0.981
dnaE
DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.980
dnaX
DNA polymerase III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.977
ACS38179.1
Hypothetical protein, putative exonuclease domain; No homology to any previously reported sequences.
    
 0.956
dnaQ
DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
    
 0.956
ACS39341.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
    0.872
ACS42491.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.793
dnaE-2
Error-prone DNA polymerase, DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
  
 
 0.784
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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