node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40262.1 | argD | MexAM1_META1p2483 | MexAM1_META1p4464 | Putative aminotransferase (putative ybdL); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.913 |
ACS40262.1 | dapD | MexAM1_META1p2483 | MexAM1_META1p1465 | Putative aminotransferase (putative ybdL); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | 0.915 |
ACS40262.1 | dapE | MexAM1_META1p2483 | MexAM1_META1p1527 | Putative aminotransferase (putative ybdL); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.904 |
argC | argD | MexAM1_META1p4920 | MexAM1_META1p4464 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.991 |
argC | dapE | MexAM1_META1p4920 | MexAM1_META1p1527 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.535 |
argD | ACS40262.1 | MexAM1_META1p4464 | MexAM1_META1p2483 | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Putative aminotransferase (putative ybdL); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.913 |
argD | argC | MexAM1_META1p4464 | MexAM1_META1p4920 | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.991 |
argD | dapD | MexAM1_META1p4464 | MexAM1_META1p1465 | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | 0.930 |
argD | dapE | MexAM1_META1p4464 | MexAM1_META1p1527 | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.927 |
atpG | atpH | MexAM1_META1p1360 | MexAM1_META1p1362 | ATP synthase F1 sector gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | Putative ATP synthase delta chain (atpH); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. | 0.999 |
atpG | dapE | MexAM1_META1p1360 | MexAM1_META1p1527 | ATP synthase F1 sector gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.529 |
atpH | atpG | MexAM1_META1p1362 | MexAM1_META1p1360 | Putative ATP synthase delta chain (atpH); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. | ATP synthase F1 sector gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | 0.999 |
atpH | dapE | MexAM1_META1p1362 | MexAM1_META1p1527 | Putative ATP synthase delta chain (atpH); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.563 |
atpH | prfB | MexAM1_META1p1362 | MexAM1_META1p3187 | Putative ATP synthase delta chain (atpH); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.612 |
dapD | ACS40262.1 | MexAM1_META1p1465 | MexAM1_META1p2483 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | Putative aminotransferase (putative ybdL); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.915 |
dapD | argD | MexAM1_META1p1465 | MexAM1_META1p4464 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.930 |
dapD | dapE | MexAM1_META1p1465 | MexAM1_META1p1527 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | N-succinyl-diaminopimelate deacylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.854 |
dapD | dapF | MexAM1_META1p1465 | MexAM1_META1p2917 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.457 |
dapD | trx | MexAM1_META1p1465 | MexAM1_META1p2247 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | Thioredoxin; Function of strongly homologous gene; carrier. | 0.742 |
dapD | trx-2 | MexAM1_META1p1465 | MexAM1_META1p4886 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. | Thioredoxin; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thioredoxin family. | 0.754 |