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pck pck pdhB pdhB pyk-2 pyk-2 aspA aspA gltA gltA pyk pyk ppc ppc ACS42227.1 ACS42227.1 mdh mdh pdhC pdhC pdhA pdhA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pckPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.974
pyk-2
Pyruvate kinase; Function of strongly homologous gene; enzyme.
     
 0.966
aspA
Aspartate ammonia-lyase (Aspartase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.960
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 
 0.956
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
     
 0.950
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.949
ACS42227.1
Succinate-semialdehyde dehydrogenase I, NADP-dependent (gabD-like); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.945
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
 
 
 0.937
pdhC
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.934
pdhA
Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.931
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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