node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38419.1 | ACS39347.1 | MexAM1_META1p0478 | MexAM1_META1p1485 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.946 |
ACS38419.1 | ACS42031.1 | MexAM1_META1p0478 | MexAM1_META1p4398 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | 0.484 |
ACS38419.1 | aroA | MexAM1_META1p0478 | MexAM1_META1p2118 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.872 |
ACS38419.1 | aroB | MexAM1_META1p0478 | MexAM1_META1p1535 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.934 |
ACS38419.1 | aroC | MexAM1_META1p0478 | MexAM1_META1p3197 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
ACS38419.1 | aroE | MexAM1_META1p0478 | MexAM1_META1p1380 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.508 |
ACS38419.1 | aroG | MexAM1_META1p0478 | MexAM1_META1p1974 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-dehydro-3-deoxyphosphoheptonate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.840 |
ACS38419.1 | aroK | MexAM1_META1p0478 | MexAM1_META1p2101 | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative shikimate kinase with helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.864 |
ACS39347.1 | ACS38419.1 | MexAM1_META1p1485 | MexAM1_META1p0478 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.946 |
ACS39347.1 | aroA | MexAM1_META1p1485 | MexAM1_META1p2118 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.987 |
ACS39347.1 | aroB | MexAM1_META1p1485 | MexAM1_META1p1535 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.896 |
ACS39347.1 | aroC | MexAM1_META1p1485 | MexAM1_META1p3197 | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.847 |
ACS42031.1 | ACS38419.1 | MexAM1_META1p4398 | MexAM1_META1p0478 | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.484 |
ACS42031.1 | aroA | MexAM1_META1p4398 | MexAM1_META1p2118 | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.789 |
ACS42031.1 | aroB | MexAM1_META1p4398 | MexAM1_META1p1535 | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.877 |
ACS42031.1 | aroC | MexAM1_META1p4398 | MexAM1_META1p3197 | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.874 |
ACS42031.1 | aroE | MexAM1_META1p4398 | MexAM1_META1p1380 | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | Putative shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.433 |
aroA | ACS38419.1 | MexAM1_META1p2118 | MexAM1_META1p0478 | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.872 |
aroA | ACS39347.1 | MexAM1_META1p2118 | MexAM1_META1p1485 | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative cyclohexadienyl dehydrogenase (tyrC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.987 |
aroA | ACS42031.1 | MexAM1_META1p2118 | MexAM1_META1p4398 | 3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Conserved hypothetical protein with putative prephenate/arogenate dehydrogenase domain; Homologs of previously reported genes of unknown function. | 0.789 |