node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
mcmA | pdhC | MexAM1_META1p5251 | MexAM1_META1p2989 | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.831 |
mcmA | sdhB | MexAM1_META1p5251 | MexAM1_META1p3863 | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Succinate dehydrogenase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.425 |
mcmA | sucB | MexAM1_META1p5251 | MexAM1_META1p1541 | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.831 |
mcmA | sucC | MexAM1_META1p5251 | MexAM1_META1p1538 | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.934 |
mcmA | sucD | MexAM1_META1p5251 | MexAM1_META1p1539 | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.939 |
mtkA | pdhC | MexAM1_META1p1730 | MexAM1_META1p2989 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.826 |
mtkA | sdhA/B | MexAM1_META1p1730 | MexAM1_META1p3861 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.850 |
mtkA | sdhB | MexAM1_META1p1730 | MexAM1_META1p3863 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.872 |
mtkA | sdhC | MexAM1_META1p1730 | MexAM1_META1p3859 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase, cytochrome b556 subunit; Function of strongly homologous gene; enzyme. | 0.859 |
mtkA | sdhD | MexAM1_META1p1730 | MexAM1_META1p3860 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase delta subunit; Function of strongly homologous gene; enzyme. | 0.850 |
mtkA | sucA | MexAM1_META1p1730 | MexAM1_META1p1540 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.906 |
mtkA | sucB | MexAM1_META1p1730 | MexAM1_META1p1541 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.866 |
mtkA | sucD | MexAM1_META1p1730 | MexAM1_META1p1539 | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.999 |
pdhC | mcmA | MexAM1_META1p2989 | MexAM1_META1p5251 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | methylmalonyl-CoA mutase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.831 |
pdhC | mtkA | MexAM1_META1p2989 | MexAM1_META1p1730 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | 0.826 |
pdhC | sdhA/B | MexAM1_META1p2989 | MexAM1_META1p3861 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.671 |
pdhC | sdhB | MexAM1_META1p2989 | MexAM1_META1p3863 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.826 |
pdhC | sdhC | MexAM1_META1p2989 | MexAM1_META1p3859 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556 subunit; Function of strongly homologous gene; enzyme. | 0.547 |
pdhC | sucA | MexAM1_META1p2989 | MexAM1_META1p1540 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.980 |
pdhC | sucC | MexAM1_META1p2989 | MexAM1_META1p1538 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.963 |