node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41485.1 | ACS42101.1 | MexAM1_META1p3791 | MexAM1_META1p4470 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.803 |
ACS41485.1 | icd | MexAM1_META1p3791 | MexAM1_META1p3354 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | NADP-dependent isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.441 |
ACS41485.1 | lpd | MexAM1_META1p3791 | MexAM1_META1p1542 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.803 |
ACS41485.1 | lpd-2 | MexAM1_META1p3791 | MexAM1_META1p2990 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Dihydrolipoamide dehydrogenase, E3 Component of Pyruvate dehydrogenase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.803 |
ACS41485.1 | pdhB | MexAM1_META1p3791 | MexAM1_META1p2987 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.967 |
ACS41485.1 | sucA | MexAM1_META1p3791 | MexAM1_META1p1540 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.967 |
ACS41485.1 | sucC | MexAM1_META1p3791 | MexAM1_META1p1538 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.795 |
ACS41485.1 | sucD | MexAM1_META1p3791 | MexAM1_META1p1539 | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.759 |
ACS42101.1 | ACS41485.1 | MexAM1_META1p4470 | MexAM1_META1p3791 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.803 |
ACS42101.1 | lpd | MexAM1_META1p4470 | MexAM1_META1p1542 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.928 |
ACS42101.1 | lpd-2 | MexAM1_META1p4470 | MexAM1_META1p2990 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide dehydrogenase, E3 Component of Pyruvate dehydrogenase multienzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.928 |
ACS42101.1 | pdhB | MexAM1_META1p4470 | MexAM1_META1p2987 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
ACS42101.1 | pdhC | MexAM1_META1p4470 | MexAM1_META1p2989 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.992 |
ACS42101.1 | sucA | MexAM1_META1p4470 | MexAM1_META1p1540 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.982 |
ACS42101.1 | sucB | MexAM1_META1p4470 | MexAM1_META1p1541 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.990 |
ACS42101.1 | sucC | MexAM1_META1p4470 | MexAM1_META1p1538 | Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.437 |
icd | ACS41485.1 | MexAM1_META1p3354 | MexAM1_META1p3791 | NADP-dependent isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Putative biotin/lipoyl attachment domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.441 |
icd | pdhB | MexAM1_META1p3354 | MexAM1_META1p2987 | NADP-dependent isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.575 |
icd | pdhC | MexAM1_META1p3354 | MexAM1_META1p2989 | NADP-dependent isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.441 |
icd | sucA | MexAM1_META1p3354 | MexAM1_META1p1540 | NADP-dependent isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 2-oxoglutarate dehydrogenase complex, E1 component, 2-oxoglutarate decarboxylase, thiamine binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.983 |