node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39432.1 | ACS39433.1 | MexAM1_META1p1571 | MexAM1_META1p1572 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.949 |
ACS39432.1 | ACS39434.1 | MexAM1_META1p1571 | MexAM1_META1p1573 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.793 |
ACS39432.1 | ACS40368.1 | MexAM1_META1p1571 | MexAM1_META1p2593 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.785 |
ACS39432.1 | mutM | MexAM1_META1p1571 | MexAM1_META1p4436 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.650 |
ACS39432.1 | radA | MexAM1_META1p1571 | MexAM1_META1p4318 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.549 |
ACS39432.1 | uvrC | MexAM1_META1p1571 | MexAM1_META1p3083 | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.461 |
ACS39433.1 | ACS39432.1 | MexAM1_META1p1572 | MexAM1_META1p1571 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.949 |
ACS39433.1 | ACS39434.1 | MexAM1_META1p1572 | MexAM1_META1p1573 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.796 |
ACS39434.1 | ACS39432.1 | MexAM1_META1p1573 | MexAM1_META1p1571 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.793 |
ACS39434.1 | ACS39433.1 | MexAM1_META1p1573 | MexAM1_META1p1572 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.796 |
ACS40368.1 | ACS39432.1 | MexAM1_META1p2593 | MexAM1_META1p1571 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.785 |
mutM | ACS39432.1 | MexAM1_META1p4436 | MexAM1_META1p1571 | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.650 |
mutM | uvrC | MexAM1_META1p4436 | MexAM1_META1p3083 | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.813 |
radA | ACS39432.1 | MexAM1_META1p4318 | MexAM1_META1p1571 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.549 |
radA | uvrC | MexAM1_META1p4318 | MexAM1_META1p3083 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.713 |
uvrC | ACS39432.1 | MexAM1_META1p3083 | MexAM1_META1p1571 | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | ATP-dependent helicase; Function of strongly homologous gene; enzyme. | 0.461 |
uvrC | mutM | MexAM1_META1p3083 | MexAM1_META1p4436 | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.813 |
uvrC | radA | MexAM1_META1p3083 | MexAM1_META1p4318 | DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.713 |