ACS39433.1 protein (Methylorubrum extorquens)

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second shell of interactors

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[Homology]

Score

ACS39433.1

Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (449 aa)

Predicted Functional Partners:

ACS39432.1

0.949

ACS39434.1

0.796

ACS40367.1

0.785

metAS

0.776

metF

0.755

metK

0.652

mntR

0.646

metH

0.432

Your Current Organism:

Methylorubrum extorquens

NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACS39432.1	ACS39433.1	MexAM1_META1p1571	MexAM1_META1p1572	ATP-dependent helicase; Function of strongly homologous gene; enzyme.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.949
ACS39432.1	ACS39434.1	MexAM1_META1p1571	MexAM1_META1p1573	ATP-dependent helicase; Function of strongly homologous gene; enzyme.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.793
ACS39433.1	ACS39432.1	MexAM1_META1p1572	MexAM1_META1p1571	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	ATP-dependent helicase; Function of strongly homologous gene; enzyme.	0.949
ACS39433.1	ACS39434.1	MexAM1_META1p1572	MexAM1_META1p1573	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.796
ACS39433.1	ACS40367.1	MexAM1_META1p1572	MexAM1_META1p2592	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	DEAD/DEAH box helicase domain protein; Function of strongly homologous gene; enzyme.	0.785
ACS39433.1	metAS	MexAM1_META1p1572	MexAM1_META1p5056	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	0.776
ACS39433.1	metF	MexAM1_META1p1572	MexAM1_META1p1493	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	0.755
ACS39433.1	metH	MexAM1_META1p1572	MexAM1_META1p1494	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.432
ACS39433.1	metK	MexAM1_META1p1572	MexAM1_META1p3521	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.652
ACS39433.1	mntR	MexAM1_META1p1572	MexAM1_META1p3854	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	DNA-binding transcriptional regulator of mntH; Function of homologous gene experimentally demonstrated in an other organism; regulator.	0.646
ACS39434.1	ACS39432.1	MexAM1_META1p1573	MexAM1_META1p1571	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	ATP-dependent helicase; Function of strongly homologous gene; enzyme.	0.793
ACS39434.1	ACS39433.1	MexAM1_META1p1573	MexAM1_META1p1572	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.796
ACS40367.1	ACS39433.1	MexAM1_META1p2592	MexAM1_META1p1572	DEAD/DEAH box helicase domain protein; Function of strongly homologous gene; enzyme.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.785
metAS	ACS39433.1	MexAM1_META1p5056	MexAM1_META1p1572	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.776
metAS	metF	MexAM1_META1p5056	MexAM1_META1p1493	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	0.897
metAS	metH	MexAM1_META1p5056	MexAM1_META1p1494	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.896
metAS	metK	MexAM1_META1p5056	MexAM1_META1p3521	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.798
metF	ACS39433.1	MexAM1_META1p1493	MexAM1_META1p1572	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.755
metF	metAS	MexAM1_META1p1493	MexAM1_META1p5056	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.	0.897
metF	metH	MexAM1_META1p1493	MexAM1_META1p1494	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.997