node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39487.1 | ACS39490.1 | MexAM1_META1p1638 | MexAM1_META1p1641 | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | 0.927 |
ACS39487.1 | ACS39498.1 | MexAM1_META1p1638 | MexAM1_META1p1649 | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.976 |
ACS39487.1 | ACS39918.1 | MexAM1_META1p1638 | MexAM1_META1p2123 | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Creatininase (creatine amidohydrolase); Function of strongly homologous gene; enzyme. | 0.907 |
ACS39487.1 | ACS41752.1 | MexAM1_META1p1638 | MexAM1_META1p4099 | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Creatininase; Function of strongly homologous gene; enzyme. | 0.929 |
ACS39490.1 | ACS39487.1 | MexAM1_META1p1641 | MexAM1_META1p1638 | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.927 |
ACS39490.1 | ACS39498.1 | MexAM1_META1p1641 | MexAM1_META1p1649 | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.833 |
ACS39490.1 | ACS39918.1 | MexAM1_META1p1641 | MexAM1_META1p2123 | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | Creatininase (creatine amidohydrolase); Function of strongly homologous gene; enzyme. | 0.786 |
ACS39490.1 | ACS41752.1 | MexAM1_META1p1641 | MexAM1_META1p4099 | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | Creatininase; Function of strongly homologous gene; enzyme. | 0.502 |
ACS39498.1 | ACS39487.1 | MexAM1_META1p1649 | MexAM1_META1p1638 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.976 |
ACS39498.1 | ACS39490.1 | MexAM1_META1p1649 | MexAM1_META1p1641 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | 0.833 |
ACS39498.1 | ACS39918.1 | MexAM1_META1p1649 | MexAM1_META1p2123 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Creatininase (creatine amidohydrolase); Function of strongly homologous gene; enzyme. | 0.969 |
ACS39498.1 | ACS41752.1 | MexAM1_META1p1649 | MexAM1_META1p4099 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Creatininase; Function of strongly homologous gene; enzyme. | 0.930 |
ACS39498.1 | deoA | MexAM1_META1p1649 | MexAM1_META1p3168 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.926 |
ACS39498.1 | rutA | MexAM1_META1p1649 | MexAM1_META1p1664 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative luciferase family protein, putative flavin-dependent oxidoreductase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.900 |
ACS39498.1 | rutF | MexAM1_META1p1649 | MexAM1_META1p1660 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | rutF-2 | MexAM1_META1p1649 | MexAM1_META1p3229 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | upp | MexAM1_META1p1649 | MexAM1_META1p1439 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.945 |
ACS39498.1 | xapA | MexAM1_META1p1649 | MexAM1_META1p3170 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
ACS39918.1 | ACS39487.1 | MexAM1_META1p2123 | MexAM1_META1p1638 | Creatininase (creatine amidohydrolase); Function of strongly homologous gene; enzyme. | Putative creatininase (creatine amidohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.907 |
ACS39918.1 | ACS39490.1 | MexAM1_META1p2123 | MexAM1_META1p1641 | Creatininase (creatine amidohydrolase); Function of strongly homologous gene; enzyme. | Conserved hypothetical protein with putative FAD binding domain; Homologs of previously reported genes of unknown function. | 0.786 |