node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40957.1 | ACS41365.1 | MexAM1_META1p3211 | MexAM1_META1p3654 | Putative aminomutase, putative kamA and yjeK-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.803 |
ACS40957.1 | lysA | MexAM1_META1p3211 | MexAM1_META1p1718 | Putative aminomutase, putative kamA and yjeK-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.803 |
ACS41365.1 | ACS40957.1 | MexAM1_META1p3654 | MexAM1_META1p3211 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative aminomutase, putative kamA and yjeK-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.803 |
ACS41365.1 | asdB | MexAM1_META1p3654 | MexAM1_META1p2896 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.700 |
ACS41365.1 | ask | MexAM1_META1p3654 | MexAM1_META1p0732 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Aspartate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.964 |
ACS41365.1 | dapA | MexAM1_META1p3654 | MexAM1_META1p3403 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.873 |
ACS41365.1 | dapB | MexAM1_META1p3654 | MexAM1_META1p2473 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.791 |
ACS41365.1 | dapF | MexAM1_META1p3654 | MexAM1_META1p2917 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.949 |
ACS41365.1 | hom | MexAM1_META1p3654 | MexAM1_META1p1941 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.532 |
ACS41365.1 | lysA | MexAM1_META1p3654 | MexAM1_META1p1718 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.925 |
ACS41365.1 | murE | MexAM1_META1p3654 | MexAM1_META1p5087 | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.919 |
asdB | ACS41365.1 | MexAM1_META1p2896 | MexAM1_META1p3654 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.700 |
asdB | ask | MexAM1_META1p2896 | MexAM1_META1p0732 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.997 |
asdB | dapA | MexAM1_META1p2896 | MexAM1_META1p3403 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.984 |
asdB | dapB | MexAM1_META1p2896 | MexAM1_META1p2473 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.859 |
asdB | dapF | MexAM1_META1p2896 | MexAM1_META1p2917 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.876 |
asdB | hom | MexAM1_META1p2896 | MexAM1_META1p1941 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.975 |
asdB | lysA | MexAM1_META1p2896 | MexAM1_META1p1718 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.587 |
asdB | murE | MexAM1_META1p2896 | MexAM1_META1p5087 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.426 |
ask | ACS41365.1 | MexAM1_META1p0732 | MexAM1_META1p3654 | Aspartate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.964 |