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xoxF xoxF xoxG xoxG fae-2 fae-2 fae fae xoxJ xoxJ fae-3 fae-3 mxaI mxaI mauB mauB mauA mauA soxG soxG ACS39408.1 ACS39408.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
xoxFXoxF, PQQ-linked dehydrogenase of unknown function; Simiilar to methanol dehydrogenase large subunit lacking methanol dehydrogenase activity; Function of strongly homologous gene; enzyme. (601 aa)    
Predicted Functional Partners:
xoxG
Function of strongly homologous gene; enzyme.
 
  
 0.971
fae-2
Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin, a reaction which also proceeds spontaneously, but at a lower rate than that of the enzyme-catalyzed reaction. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium.
  
  
 0.970
fae
Formaldehyde activating enzyme-like protein; Function of strongly homologous gene; putative enzyme.
  
  
 0.964
xoxJ
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.963
fae-3
Formaldehyde activating enzyme-like protein; Function of strongly homologous gene; putative enzyme.
     
 0.959
mxaI
Methanol dehydrogenase subunit 2 precursor (MDH small beta subunit); Catalyzes the oxidation of primary alcohols including methanol; Belongs to the methanol dehydrogenase subunit 2 family.
 
 
 
 0.921
mauB
Methylamine dehydrogenase large subunit precursor (MADH); Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin; Belongs to the aromatic amine dehydrogenase heavy chain family.
 
 
  0.915
mauA
Methylamine dehydrogenase small subunit precursor (MADH); Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin; Belongs to the aromatic amine dehydrogenase light chain family.
  
  
  0.914
soxG
Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme.
     
  0.900
ACS39408.1
Putative Sarcosine oxidase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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